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Ecosystems Research

Chris Mazur

My current research focuses on the in vitro metabolism of foreign chemicals, using microsomal assays and hepatocyte cell culture; developing saturation kinetic profiles; characterizing enzymes; and determining biotransformation/transport pathways.

Biographical Information

Name: Christopher S. Mazur
Title: Research Biologist

Contact Info:

Ecosystems Research Division
National Exposure Research Laboratory
Office of Research and Development
U.S. Environmental Protection Agency
960 College Station Road
Athens, Georgia 30605-2700

Phone: 706-355-8233
Email: mazur.chris@epa.gov

Education

M.S. Zoology and Physiology/Water Resource Division, University of Wyoming, 1995
B.A. Environmental Science/Biology, Mansfield University, 1993

Professional Experience

Research Biologist, USEPA, ORD, NERL-ERD, Athens, GA 1996–present

Selected Awards and Honors

USEPA, STAA Award, Level III, 2002, 2003, 2006, 2009, 2010, 2011
USEPA STAA Awards Honorable Mention 2004, 2008
University of Wyoming, Fall Teaching Assistantship Award, 1989
Oakridge Institute for Science and Education, Fellowship Award, 1996-1998

Selected Publications

Mazur, C.S., Marchitti, S.A., Dimova, M., Kenneke, J.F., Lumen, A., Fisher, J. 2012. Human and rat ABC transporter efflux of Bisphenol A and Bishpenol A glucoronide: interspecies comparison and implications for pharmacokinetic assessment. (Toxicological Sciences, 128:317-325)

Mazur, C.S., Kenneke, J.F., Hess-Wilson, J.K., Lipscomb, J.C. 2010. Differences between human and rat intestinal and hepatic Bisphenol A glucuronidation and the influence of alamethicin on in vitro kinetic measurements. Drug Metabolism and Disposition, 38:2232-2238

Mazur,C.S., Kenneke, J.F., Goldsmith, M.R., Brown, C.C. 2009. Contrasting influence of NADPH and a NADPH-regenerating system on the metabolism of carbonyl-containing compounds in hepatic microsomes. Drug Metabolism and Disposition, 37:1801-1805.

Mazur, C.S., Kenneke, J.F. 2008. Cross-species comparison of conazole fungicide metabolites using rat and rainbow trout (Onchorhynchus mykiss) hepatic microsomses and purified CYP 3A4. Environmental Science and Technology, 42:947-954.

Mazur, C.S., J.F. Kenneke, C.T. Tebes-Stevens, M.S. Okino and J.C. Lipscomb. 2007. In Vitro Metabolism of the Fungicide and Environmental Contaminant trans-bromuconazole and Implications for Risk Assessment. Journal of Toxicology and Environmental Health, Part A. 70:1241-1250.

Publications and Presentations

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esults.cfm?fed_org_id=770&SIType=PR&TIMSType=&showCriteria=0&address=nerl/pubs.html&view=citation&personID=18085&role=Author&sortBy=pubDateYear&count=100&dateBeginPublishedPresented=">Publications & Presented Research Bouchard, Dermont Physical Scientist Publications & Presented Research Burke, Roger Research Chemist Publications & Presented Research Collette, Timothy W Research Chemist Publications & Presented Research Colón, Dalizza Research Chemist Publications & Presented Research Cyterski, Mike Research Ecologist Publications & Presented Research Ekman, Drew Research Chemist Publications & Presented Research Gabriel, Mark C Environmental Engineer Publications & Presented Research Galvin, Mike Computer Scientist Publications & Presented Research Garrison, Arthur W Research Chemist Publications & Presented Research Henderson, William M Research Toxicologist Publications & Presented Research Hilal, Said Research Chemist Publications & Presented Research Kenneke, John Research Chemist Publications & Presented Research Kitchens, Brenda E Environmental Scientist Publications & Presented Research Knightes, Chris Environmental Engineer Publications & Presented Research Kraemer, Stephen R Research Hydrologist Publications & Presented Research Laniak, Gerard F Environmental Engineer Publications & Presented Research Mazur, Christopher S Research Biologist Publications & Presented Research McCutcheon, Steven C Research Environmental Engineer Publications & Presented Research Mohamoud, Yusuf Research Hydrologist Publications & Presented Research Molina, Marirosa Microbiologist Publications & Presented Research Parmar, Rajbir Computer Engineer Publications & Presented Research Prieto, Lourdes M Environmental Scientist Publications & Presented Research Purucker, Thomas S Research Ecologist Publications & Presented Research Richardson, Susan D Research Chemist Publications & Presented Research Spidle, David L Research Chemist Publications & Presented Research Stevens, Caroline Environmental Engineer Publications & Presented Research Suárez, Luis Research Pharmacologist Publications & Presented Research Teng, Quincy Research Chemist Publications & Presented Research Washington, John W Research Chemist Publications & Presented Research Weber, Eric J Research Chemist Publications & Presented Research Whelan, Gene Research Engineer Publications & Presented Research Wolfe, Kurt L Computer Engineer Publications & Presented Research Zepp, Richard G Senior Research Scientist Publications & Presented Research Post-Doctoral Scientist Name/Short Bio Title Publications & Presented Research
(1999-Present) Bradshaw, James (ORISE) ORISE Post-doctoral Researcher Gabriel, Mark C. Environmental Engineer Ghimire, Santosh (ORISE) ORISE Post-doctoral Researcher Hong, Tao (ORISE) ORISE Post-doctoral Researcher Marchitti, Satori Toxicologist Naile, Jonathan Toxicologist Price, Katie Geographer Skelton, David Geographer Sola-Soto, Hilda M Chemist Van Meter, Robin (ORISE) ORISE Post-doctoral Researcher Wong, Kelvin Physical Scientist Technical Support Staff Name/Short Bio Title Publications & Presented Research
(1999-Present)

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