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NCCT Welcomes Two Scientists to our Fellowship Program
Dr. Robert Dewoskin
Dr. Peter Egeghy
(Research Triangle Park, N.C., -- June 17, 2009) NCCT welcomes Drs. Egeghy and DeWoskin on a scientist rotation for the next four to six months in The Computational Toxicology Rotational Fellowship Program. Dr. Peter Egeghy comes to us from the National Exposure Research Laboratory and Robert Dewoskin comes to us from the National Center for Environmental Assessment.
Dr. Egeghy will be working with Dr. Cohen Hubal on the ExpoCast™ Program. ExpoCast™ is being initiated to ensure the required exposure science and computational tools are ready to address global needs for rapid characterization of exposure potential arising from the manufacture and use of tens of thousands of chemicals. An important early component of ExpoCast™ will be to consider how best to consolidate and link human exposure data for chemical prioritization and toxicity testing. Dr. Egeghy will help identify high priority human exposure data resources for initial chemical indexing in collaboration with ACToR and DSSTox, lead development of standards for exposure data representation, and direct initial implementation of these standards for the most critical data. As a fellow with the NCCT, Dr. Egeghy will foster the cross-ORD collaborations required to facilitate progress on these activities.
Dr. DeWoskin will be working on an integrated multidisciplinary project with Dr. Knudsen to develop an agent-based model that simulates cellular changes leading to pattern disruption in limb formation, as part of EPA's Virtual Embryo project (http://www.epa.gov/ncct/v-Embryo/). This research fellowship will provide research experience in newer technologies for predictive modeling of developmental toxicity, as well as training in other complimentary areas of NCCT research including the application of systems-based in vitro assays and machine-learning algorithms to derive cell signaling networks and build functional models for pathway-based risk assessment. As a fellow with the NCCT, Dr. DeWoskin will foster the cross-ORD collaborations and advance NCEA's understanding of the latest data and methods for quantitative characterization of the Mode of Action.