Endocrine Disruptor Research Project Level Inventory
Breakdown by Federal Agency Involvement
Primary Sponsor: EPA

Human: (28)

• PROTECTIVE INFLUENCE OF MELATONIN ON CANCER CAUSED BY ENDOCRINE DISRUPTERS
• RAPID SCREENING PROCEDURE TO IDENTIFY ENDOCRINE DISRUPTERS
• EVALUATION OF THE ROLE OF ENDOCRINE DISRUPTION IN HEPATOCELLULAR CARCINOGENESIS INDUCED BY DRINKING WATER DISINFECTION BY-PRODUCTS (DBPS).
• INTERACTION OF CHEMICALS AND ENDOCRINE RECEPTORS/ MOLECULAR MODELS
• DEVELOPMENT AND VALIDATION OF TOXIC EQUIVALENCY FACTORS FOR DIOXIN LIKE CHEMICALS
• DEVELOPMENT AND VALIDATION OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELS FOR DIOXINS.
• THE EFFECTS OF TCDD ON TRANSGENIC MICE MISSING EITHER THE AH RECEPTOR OR CYP1A2
• DISPOSITION AND PHARMACOKINETICS OF DIOXINS IN PREGNANT AND FETAL RATS.
• CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVE DEVELOPMENT: IN VIVO EFFECTS OF ENVIRONMENTAL ANTIANDROGENS
• UTERINE FUNCTION/TOXIC EFFECTS
• EFFECTS OF PCBS ON COGNITIVE FUNCTION IN RATS
• THE OTOTOXICITY OF DEVELOPMENTAL EXPOSURE TO POLYCHLORINATED BIPHENYLS
• NEUROTOXICITY OF POLYCHLORINATED BIPHENYLS AND RELATED CHEMICALS: STRUCTURE-ACTIVITYRELATIONSHIPS AND MODELS
• DEVELOPMENTAL EXPOSURE TO DIOXIN/PCBS AND FUNCTION OF THE HYPOTHALAMIC-PITUITARYADRENAL (HPA) AXIS
• THE NEUROPROTECTIVE ACTIONS OF ESTROGEN AND THEIR DISRUPTION BY ENVIRONMENTALESTROGENS
• DISRUPTION OF THYROID HORMONE ACTIONS BY ENVIRONMENTAL AGENTS - IMPACT ON BRAINDEVELOPMENT
• HOMOLOGOUS MODELS OF COGNITIVE DEVELOPMENT: EFFECTS OF HYPOTHYROIDISM.
• RECEPTOR MEDIATED DEVELOPMENTAL TOXICITY
• RELEVANCE OF ACUTE EXPOSURE AND THE DEVELOPMENT OF TOLERANCE TO REPRODUCTIVETOXICANTS.
• ENDOCRINE DISRUPTERS IN VITRO SCREEN
• REPRODUCTIVE AND ENDOCRINE EFFECTS OF ACUTE EXPOSURE TO ENVIRONMENTAL AGENTS INTHE FEMALE RODENT.
• TOXICANT-INDUCED ALTERATIONS IN OVARIAN MECHANISMS OF OVULATION.
• CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVE DEVELOPMENT: IN VIVO EFFECTS OF ENVIRONMENTAL ESTROGENS
• EFFECTS OF IN UTERO EXPOSURE TO NANOGRAM DOSES OF DIOXIN(2,3,7,8 TETRACHLORODIBENZO-P-DIOXIN) ON MALE AND FEMALE RODENT REPRODUCTIVE DEVELOPMENT: IN VIVO DEVELOPMENTAL EFFECTS OFCHEMICALS THAT BIND AH RECEPTORS.
• CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVEDEVELOPMENT
• EFFECTS OF ANDROGEN STATUS ON SPERM MATURATION
• DEVELOPMENTAL NEUROTOXICITY OF POLYCHLORINATED BIPHENYLS
• EFFECTS OF ENVIRONMENTAL TOXICANTS ON THE STEROID HORMONE PATHWAY

Ecology: (16)

• TRANSGENERATIONAL EFFECTS OF DIOXIN EXPOSURE IN THE MUMMICHOG
• DIAGNOSTIC INDICATORS OF ENDOCRINE DISRUPTION IN MARINE AND ESTUARINE FISH
• SHORT-TERM SCREENING ASSAY FOR ENDOCRINE DISRUPTORS
• EFFECT OF ENDOCRINE DISRUPTING ENVIRONMENTAL CONTAMINANTS ON EARLY DEVELOPMENT OFOVIPAROUS ESTUARINE FISH
• QSARS FOR THE IDENTIFICATION OF DEVELOPMENTAL AND REPRODUCTIVE TOXICANTS
• IN VITRO METHODS TO ASSESS REPRODUCTIVE/DEVELOPMENTAL RISK OF ENVIRONMENTAL CONTAMINANTS TO AQUATIC ORGANISMS
• INVERTEBRATE MODELS FOR ASSESSING THE DEVELOPMENTAL ANDREPRODUCTIVE EFFECTS OF CONTAMINANTS
• REPRODUCTIVE EFFECTS OF 2,3,7,8-TCDD ON FRESHWATER FISH AND INVERTEBRATES
• DEVELOPMENT OF SMALL FISH MODELS FOR ASSESSING DEVELOPMENTAL AND REPRODUCTIVE TOXICITY
• COMPARATIVE TOXICOLOGY AND ENDOCRINOLOGY OF AMPHIBIANS
• CONTAMINANT-INDUCED CHANGES IN HEPATIC STEROID HORMONE DEGRADATION
• EVALUATION OF IMMUNE FUNCTION, CHEMICAL EXPOSURE AND MORBILLIVIRUS INFECTION INBOTTLENOSE DOLPHINS FROM CLEAN VS. POLLUTED COSTAL WATERS.
• INTEGRATED ASSESSMENT OF XENOBIOTIC ENDOCRINE DISRUPTOE EFFECTS ON LIFE CYCLESOF SELECTED FISH SPECIES
• DEVELOPMENT OF AN IN-VIVO ASSAY FOR INSULIN-LIKE GROWTH FACTOR IN FISH.
• DEVELOPMENT OF AN IN VIVO ASSAY FOR FISH VITELLOGENIN INDUCTION IN FISH EXPOSED TOSYNTHETIC AND XENOESTROGENS.
• COMPARISON OF IN-VITRO YEAST ESTROGEN SYSTEM (YES) ASSAY (USING THE HUMANESTROGEN RECEPTOR - HER) AND IN-VIVO FISH VITELLOGEN ASSAY.

Exposure: (7)

• CHEMICAL BURDENS OF ENDOCRINE DISRUPTORS IN MARINE AND ESTUARINE FISH
• EVALUATION OF RESISTANCE TO TRICHINELLA SPIRALIS INFECTION IN INTACT AND GONADECTOMIZEDRODENTS EXPOSED TO TCDD.
• EFFECTS OF GESTATIONAL AND/OR LACTATIONAL EXPOSURE TO 2,3,7,8-TCDD ON IMMUNEFUNCTION IN RATS
• ANALYTICAL METHODS FOR MEASURING ENDOCRINE DISRUPTORS IN THE ENVIRONMENT
• DEVELOPMENT OF GENE PROBES FOR DIAGNOSIS OF EXPOSURE TO SEX STEROID ENDOCRINEDISRUPTORS.
• DEVELOP, SELECT AND APPLY COMPARTMENTAL MODELS FORPREDICTING EDC EXPOSURES.
• TRANSPORT AND TRANSFORMATION PROCESSES AFFECTING THE FATE OF EDCS IN SEDIMENTS AND SOILS

Secondary Focus: EPA

Human: (No projects found)

Ecology: (4)

• CHEMICAL BURDENS OF ENDOCRINE DISRUPTORS IN MARINE AND ESTUARINE FISH
• CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVE DEVELOPMENT: IN VIVO EFFECTS OF ENVIRONMENTAL ANTIANDROGENS
• CELLULAR AND MOLECULAR MECHANISMS OF ABNORMAL REPRODUCTIVE DEVELOPMENT: IN VIVO EFFECTS OF ENVIRONMENTAL ESTROGENS
• EFFECTS OF IN UTERO EXPOSURE TO NANOGRAM DOSES OF DIOXIN(2,3,7,8 TETRACHLORODIBENZO-P-DIOXIN) ON MALE AND FEMALE RODENT REPRODUCTIVE DEVELOPMENT: IN VIVO DEVELOPMENTAL EFFECTS OFCHEMICALS THAT BIND AH RECEPTORS.

Exposure: (7)

• EVALUATION OF IMMUNE FUNCTION, CHEMICAL EXPOSURE AND MORBILLIVIRUS INFECTION INBOTTLENOSE DOLPHINS FROM CLEAN VS. POLLUTED COSTAL WATERS.
• INTEGRATED ASSESSMENT OF XENOBIOTIC ENDOCRINE DISRUPTOE EFFECTS ON LIFE CYCLESOF SELECTED FISH SPECIES
• DEVELOPMENT OF AN IN-VIVO ASSAY FOR INSULIN-LIKE GROWTH FACTOR IN FISH.
• DEVELOPMENT OF AN IN VIVO ASSAY FOR FISH VITELLOGENIN INDUCTION IN FISH EXPOSED TOSYNTHETIC AND XENOESTROGENS.
• COMPARISON OF IN-VITRO YEAST ESTROGEN SYSTEM (YES) ASSAY (USING THE HUMANESTROGEN RECEPTOR - HER) AND IN-VIVO FISH VITELLOGEN ASSAY.
• NEUROTOXICITY OF POLYCHLORINATED BIPHENYLS AND RELATED CHEMICALS: STRUCTURE-ACTIVITYRELATIONSHIPS AND MODELS
• DEVELOPMENTAL NEUROTOXICITY OF POLYCHLORINATED BIPHENYLS