Hershberger Assay Peer Review Materials
The Hershberger assay was peer reviewed by the Organization for Economic Cooperation and Development (OECD). Peer review materials made available by OECD for the Hershberger Assay can be accessed below:
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Final OECD Report of the Initial Work Towards the Validation of the Rat Hershberger Assay: Phase-1: Androgenic Response To Testosterone Propionate, And Anti-Androgenic Effects of Flutamide (PDF) (209 pp, 1.8M)
Draft Report of the OECD Validation of the Rat Hershberger Bioassay: Phase-2: Testing of Androgen Agonists, Androgen Antagonists and a 5α-Reductase Inhibitor in Dose Response Studies by Multiple Laboratories (PDF) (110 pp, 780K)
Draft Report of the OECD Validation of the Rat Hershberger Bioassay: Phase 3: Coded Testing of Androgen Agonists, Androgen Antagonists and Negative Reference Chemicals by Multiple Laboratories. Surgical Castrate Model Protocol (PDF) (145 pp, 1.8M)
Report of the Validation Peer Review for the Hershberger Bioassay, and the Agreement of the Working Group of the National Coordinators of the Test Guidelines Programme on The Follow-Up of This Report (PDF) (26 pp, 249K)