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Research Product

Folmar, L.C., S. Bonomelli, T. Moody and J. Gibson. 1993. Effect of Short-Term Exposure to Three Chemicals on the Blood Chemistry of the Pinfish (Lagodon rhomboides). EPA/600/J-93/063. Arch. Environ. Contam. Toxicol. 24(1):83-86. (ERL,GB 784). (Also avail. from NTIS, Springfield, VA: PB93-168979)

Injections of 3 ml/kg CCl4 caused significant elevations in the serum enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LD-L). Serum lipids and total protein were significantly lower, while serum glucose was significantly greater. Serum protein electrophoresis showed disassociation of albumin. Seawater species appear more tolerant of nitrite intoxication than freshwater species. Concentrations of fenthion as high as 30% of the 48-hr LC50 did not inhibit serum cholinesterase or alter serum chemistry.

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