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Search by Human Carcinogenicity

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  • Search Scope:
    The search by Evidence for Human Carcinogenicity allows you to search the IRIS database to identify substances by weight-of-evidence classifications established by EPA using the 1986, 1996, 1999, and 2005 Guidelines for Carcinogen Risk Assessment. These guidelines reflect the evolution of the science in this area and the corresponding evolution of the Agency’s approach to characterizing weight-of-evidence for human carcinogenicity.

Search Cancer Descriptor by EPA Cancer Guidelines (by Year) :
(You can search using one set of guidelines or across all guidelines.)

  • Using the 1986 Guidelines  (check all that apply):
     Check All '86 Guidelines | Clear All '86 Guidelines
    A (Human carcinogen)
    B1 (Probable human carcinogen - based on limited evidence of carcinogenicity in humans and sufficient evidence of carcinogenicity in animals)
    B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals)
    C (Possible human carcinogen)
    D (Not classifiable as to human carcinogenicity)
    E (Evidence of non-carcinogenicity for humans)


  • Using the 1996 Guidelines   (check all that apply):
     Check All '96 Guidelines | Clear All '96 Guidelines
    Known/likely human carcinogen
    Carcinogenic potential cannot be determined
    Not likely to be carcinogenic to humans


  • Using the 1999 Guidelines   (check all that apply):
     Check All '99 Guidelines | Clear All '99 Guidelines
    Carcinogenic to humans
    Likely to be carcinogenic to humans
    Suggestive evidence of carcinogenicity, but not sufficient to assess human carcinogenic potential
    Data are inadequate for an assessment of human carcinogenic potential
    Not likely to be carcinogenic to humans


  • Using the 2005 Guidelines   (check all that apply):
     Check All '05 Guidelines | Clear All '05 Guidelines
    Carcinogenic to humans
    Likely to be carcinogenic to humans
    Suggestive evidence of carcinogenic potential
    Inadequate information to assess carcinogenic potential
    Not likely to be carcinogenic to humans
                            

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