Human Studies Divison
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The Human Studies Facility is equipped with many systems to study the health effects of airborne pollutants on humans. The systems can deliver gaseous pollutants at precise concentrations, across a broad range of atmospheric conditions.
Instrumentation allows researchers to measure pollutant induced changes in lung function and heart rate. All but the neurophysiological test room have exercise equipment installed, and pulmonary testing equipment is available in many exposure and test rooms throughout the building.
Gaseous exposure systems currently available include:
- 2 Large (300 sq. ft.) Rochester style rooms
- 3 Small (64 sq. ft.) Rochester style rooms
- 1 Neurophysiological test room
The facility also has two ambient-air-particle concentrators for studying the effects of concentrated particulate matter. There is also a specially designed system for exposures to diesel exhaust.
The systems currently available include:
- A coarse particle concentrator for particle sizes from 2.5 to 10 microns.
- A fine/ultra fine particle concentrator for particles 2.5 microns and smaller
- A diesel truck exhaust stream, which can be variably diluted and delivered to an exposure room
Four sets of in-vitro exposure chambers are also available for cell biology research. Participant recruitment services are available as well.
The Human Studies Facility is primarily intended for research to support EPA standards and regulations, but scientists not affiliated with EPA may use these facilities to conduct research that is in the public interest. All research using these facilities is in accord with the Common Rule for Subject Protection.
To use the facilities, non-EPA scientists must complete and Outside User Agreement with EPA. The research must address the needs of the outside user rather than EPA, and reimbursement is required for all facilities and services provided. Proposed studies must have a current Institutional Review (IRB) approval, and are subject to Agency review. Telephone contact number is 919-966-9583.
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