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Pesticide News Story: EPA Releases Test Guidelines and Schedule for Endocrine Disruptor Screening Program

For Release: October 16, 2009

As EPA prepares to order a comprehensive screening of chemical effects on hormones, the Agency is making available today the battery of scientific assays and test guidelines for conducting the assays, as well as a schedule for issuing test orders to manufacturers for each of 67 chemicals during the next three months. Now that the assays and test guidelines are available, EPA shortly will be issuing and announcing test orders to manufacturers to compel generation of the needed data.

Data required under the test orders will provide information to help EPA identify whether chemicals have the potential to interact with the estrogen, androgen, and/or thyroid hormone systems, which regulate growth, metabolism, development, and reproduction. This program, which has been developed through a multi-year research program and validated through a transparent technical review process, will eventually screen all pesticide chemicals. The data generated from the screens will provide robust and systematic scientific information that will help EPA identify and regulate as appropriate potential endocrine disrupting chemicals.

Pre-publication copies of the Notices on the assays and test guidelines and the schedule are available at http://www.epa.gov/endo/. The test guidelines are also available at http://www.epa.gov/opptsfrs/home/guidelin.htm.

The documents will publish in the Federal Register on October 21, 2009, at which time the corresponding dockets can be found on www.regulations.gov. The Federal Register document announcing the final Tier 1 battery of scientific assays and related test guidelines will be in docket number EPA–HQ–OPPT–2008–0521; the Federal Register document announcing the schedule for issuing test orders will be in docket EPA–HQ–OPP–2009–0634.


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