| Research Description |
Poster # |
Presenter(s) |
| Determine utility of emerging technologies in risk assessment |
|---|
| Application of Toxico-omics to Improving Risk Assessments - Mode of Action of Conazoles |
LTG 1-01 (PDF) (1 pg, 722KB) |
S. Nesnow and S.-F. Thai (NHEERL) |
| Use of Toxico-omics to Discriminate Conazoles and Related Chemicals from Phenobarbital for Human Relevancy Determinations in Cancer Risk Assessments |
LTG 1-02 (PDF) (1 pg, 859KB) |
S. Nesnow and S. Hester (NHEERL) |
| Develop MOA data for reproductive and developmental risks |
|---|
| Cellular and molecular modes responsible for induction of birth defects |
LTG 1-03 (PDF) (1 pg, 2.6MB) |
Sid Hunter (NHEERL) |
| Linking an in vivo pregnancy loss model to an in vitro placental cell system to explore the mode of action of disinfection byproducts |
LTG 1-04 (PDF) (1 pg, 652KB) |
Michael G. Narotsky (NHEERL) |
| The Effects of Environmental Chemicals on Neuroendocrine Function: Mode and Mechanism for Adverse Outcomes |
LTG 1-05 (PDF) (1 pg, 1.1MB) |
Ralph Cooper, Susan Laws and Tammy Stoker (NHEERL) |
| Identify PK/PD issues underlying uncertainties for extrapolation |
|---|
| How Does ORD Research on MOA Contribute to the Human Health Risk Assessment for PBDE Mixtures? |
LTG 1-06 (PDF) (1 pg, 981KB) |
Prasada Kodavanti (NHEERL) |
| Mode of action research of arsenic-induced tumors and toxicity |
LTG 1-07 (PDF) (1 pg, 945KB) |
Kirk Kitchin (NHEERL) |
| Arsenical Metabolism and Dosimetry: The Bridge Between Arsenic Exposure and Health Effects |
LTG 1-08 (PDF) (1 pg, 1.3MB) |
David J. Thomas, Elaina M. Kenyon, and Hisham El-Masri (NHEERL) |
| Develop MOA for oxidative stress in cancer and noncancer risk assessments |
|---|
| Progress toward the use of oxidative stress as a broadly applicable key event in environmental toxicity |
LTG 1-09 (PDF) (1 pg, 1.1MB) |
Gary Hatch and Prasada Kodavanti (NHEERL) |
| Future applications of Oxidative and other Stress Pathway assays to Mode of Action Studies |
LTG 1-10 (PDF) (1 pg, 1.4MB) |
Ram Ramabhadran, Steve Simmons and Gary Hatch (NHEERL) |
| Establish systems-based models for use in risk assessments |
|---|
| Systems Biology and Toxicity Testing in the Twenty-first Century |
LTG 1-11 (PDF) (1 pg, 1.1MB) |
Stephen Edwards (NHEERL) and Jerry Blancato (NCCT) |
| Development of Virtual Tissue Models |
LTG 1-12 (PDF) (1 pg, 823KB) |
Michael DeVito (NHEERL) and Imran Shah (NCCT) |
| Development and Use of Biologically-Based Dose Response (BBDR) Models |
LTG 1-13 (PDF) (1 pg, 693KB) |
Hisham El-Masri (NHEERL) and Rory Conolly (NCCT) |
| Constructing a Biologically-based Dose Response (BBDR) Model to Refine Risk Assessment Approaches to Respiratory Effects from Inhaled Reactive Gases: Chlorine |
LTG 1-14 (PDF) (1 pg, 810KB) |
Annie M. Jarabek (NHEERL/NCEA) |
![[logo] US EPA](http://www.epa.gov/epafiles/images/logo_epaseal.gif){kind=logo}