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Acceptable Substitutes in Household Refrigerators and Freezers

Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is also available.

Unacceptable substitutes   GWPs and ODPs of Some Refrigerants Used in Household Refrigerators and Freezers 

Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.

Acceptable Substitutes for CFCs (class I ODS) in Household Refrigerators and Freezers

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New
HCFC-22   12, 502 R, N
HFC-134a   12 R, N
HFC-152a   12 N
R-401A, R-401B MP-39, MP-66 12 R, N
R-402A, R-402B HP-80, HP-81 502 R, N
R-404A HP-62 502 R, N
R-406A GHG 12, 500 R
R-409A (HCFC Blend Gamma)   12 R
Free Zone (HCFC Blend Delta) Free Zone / RB-276 12 R, N
Freeze 12 Freeze 12 12 R, N
FRIGC FR-12 (HCFC Blend Beta) FRIGC FR-12 12 R, N
GHG-X4 GHG-X4, Autofrost, Chill-it 12, 500 R, N
GHG-X5 GHG-X5 12, 500 R, N
GHG-HP (HCFC Blend Lambda) GHG-HP 12 R, N
Hot Shot Hot Shot, Kar Kool 12, 500 R, N
THR-01   12 N
THR-04   502 R, N
HCFC-22/HCFC-142b   12 R, N
Ammonia Absorption   12 N
Self-chilling cans using CO2   12, 500, 502 N
Ikon B   12 N
Ikon A   12 N
THR-02   12 N
FOR12A FOR12A 12 R, N
FOR12B FOR12B 12 R, N
SP34E SP34E 12 R, N
RS-24 (2002 formulation)   12 R, N
R-407C Suva 407C, Klea 407C 502 R, N
R-420A Choice R-420A 12, 500 R, N
R-421B Choice R421B 12, 502 R, N
R-426A RS-24 12 R, N
R-422C ICOR XLT1 502 R, N
R-428A RS-52 502 R, N
KDD6 KDD6 12 R, N
Key: R = Retrofit Uses, N = New Uses

Substitutes Acceptable Subject to Use Conditions for CFCs (class I ODS) in Household Refrigerators and Freezers

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New Link to Use Conditions
Isobutane (R-600a)   12 N See SNAP rule 17
R-441A HCR-188C 12 N See SNAP rule 17  

Acceptable Substitutes for HCFC-22 (class II ODS) in Household Refrigerators and Freezers

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New
R-410A AZ-20, Suva 9100, Puron 22 and blends containing HFCFs N
R-410B   22, blends containing 22 and/or 142b N
R-407C Suva 9000, Klea 66 22 and blends containing HFCFs R, N
Ammonia Absorption   22, blends containing 22 and/or 142b N
THR-03   22 N
ISCEON 59, NU-22, R-417A ISCEON 59, NU-22 22, blends containing 22 and/or 142b R, N
R-404A HP62 22 and blends containing HFCFs R, N
R-507, R-507A AZ-50 22 and blends containing HFCFs R, N
Self-chilling cans using recycled CO2   22 R, N
RS-44 (2003 formulation)   22, blends containing 22 and/or 142b R, N
ISCEON 79, R-422A ISCEON 79 22 and blends containing HFCFs R, N
R-421A Choice R421A 22, blends containing 22 and/or 142b R, N
R-421B Choice R421B 22, blends containing 22 and/or 142b R, N
R-422D ISCEON MO29 22, blends containing 22 and/or 142b R, N
R-424A RS-44 22, blends containing 22 and/or 142b R, N
R-426A RS-24 22, blends containing 22 and/or 142b R, N
KDD5, R-438A ISCEON, MO99 22, blends containing 22 and/or 142b R, N
R-434A RS-45 22, blends containing 22 and/or 142b R, N
R-428A RS-52 22, blends containing 22 R, N
R-125/290/134a/600a (55.0/1.0/42.5/1.5) ICOR AT-22 22, blends containing 22 and/or 142b R, N
R-422B XAC1, NU-22B 22, blends containing 22 and/or 142b R, N
R-422C XLT1 22, blends containing 22 and/or 142b R, N
R-427A Forane 427A 22, blends containing 22 and/or 142b R
RS-24 (2002 formulation)   22, blends containing 22 and/or 142b R, N
HFC-134a   22, blends containing 22 and/or 142b R, N
R-407F  Genetron Performax LT 22, blends containing 22 and/or 142b R, N
Key: R = Retrofit Uses, N = New Uses

Substitutes Acceptable Subject to Use Conditions for HCFCs (class II ODS) in Household Refrigerators and Freezers

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New Link to Use Conditions
Isobutane (R-600a)   22 N See SNAP rule 17
R-441A HCR-188C 22 N See SNAP rule 17  

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