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Acceptable Substitutes in Household and Light Commercial Air Conditioning

Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is also available.

Unacceptable substitutes   GWPs and ODPs of Some Refrigerants Used in Household & Light Commercial AC 

Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.

Acceptable Substitutes for CFCs (class I ODS) in Household & Light Commercial AC

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New
Evaporative/Desiccant Cooling   all CFCs N
R-407C Suva 407C, Klea 407C 502 R, N
R-422C ICOR XLT1 502 R, N
KDD6 KDD6 12 R, N
Hot Shot 2   Hot Shot 2 12, 502 R
Key: R = Retrofit Uses, N = New Uses

Acceptable Substitutes for HCFCs (class II ODS) in Household & Light Commercial AC

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New
HFC-134a   22, blends containing 22 and/or 142b N
THR-03   22 N
NOTE: this determination applies ONLY to window-unit residential AC, and not to central AC systems.
ISCEON 59, NU-22, R-417A ISCEON 59, NU-22 22, blends containing 22 and/or 142b R, N
R-410A AZ-20, Suva 9100, Puron 22 and blends containing HCFCs N
R-410B   22, blends containing 22 and/or 142b N
R-407C Suva 9000, Klea 66 22 and blends containing HCFCs R, N
R-507, R-507A AZ-50 22 and blends containing HCFCs R, N
Ammonia Absorption   22, blends containing 22 and/or 142b N
Evaporative Cooling   22, blends containing 22 and/or 142b N
Desiccant Cooling   22, blends containing 22 and/or 142b N
R-404A HP62 22 and blends containing HCFCs R, N
R-125/134a/600a (28.1/70.0/1.9) NU-22 old composition 22, blends containing 22 and/or 142b R, N
RS-44 (2003 formulation) RS-44 (2003 formulation) 22, blends containing 22 and/or 142b R, N
R-421A Choice R421A 22, blends containing 22 and/or 142b R, N
R-422D ISCEON MO29 22, blends containing 22 and/or 142b R, N
R-424A RS-44 22, blends containing 22 and/or 142b R, N
R-125/290/134a/600a (55.0/1.0/42.5/1.5) ICOR AT-22 22, blends containing 22 and/or 142b R, N
R-422C ICOR XLT1 22, blends containing 22 and/or 142b R, N
R-422B ICOR XAC1, NU-22B 22, blends containing 22 and/or 142b R, N
KDD5, R-438A ISCEON MO99 22, blends containing 22 and/or 142b R, N
R-434A RS-45 22, blends containing 22 and/or 142b R, N
R-407A KLEA 60, KLEA 407A 22 and blends containing HCFCs R, N
R-427A Forane 427A 22, blends containing 22 and/or 142b R
R-437A ISCEON MO49 Plus 22, blends containing 22 and/or 142b R, N
Hot Shot 2   Hot Shot 2 22, blends containing 22 and/or 142b R
R-407F   Genetron Performax LT 22, blends containing 22 and/or 142b R, N
Key: R = Retrofit Uses, N = New Uses

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