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Acceptable Substitutes in Refrigerated Transport
Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is also available.
Unacceptable substitutesNote: SNAP-related information published in the Federal Register takes precedence over all information on this page.
Acceptable Substitutes for CFCs (class I ODS) in Refrigerated Transport
| Substitute (Name Used in the Federal Register) | Trade Name | Refrigerant Being Replaced | Retrofit/ New |
|---|---|---|---|
| HCFC-22 | 12, 502 | R, N | |
| Ikon A | 12 | R, N | |
| Ikon B | 12 | R, N | |
| THR-02 | 12 | R, N | |
| HFC-134a | 12 | R, N | |
| R-401A, R-401B | MP-39, MP-66 | 12 | R, N |
| R-402A, R-402B | HP-80, HP-81 | 502 | R, N |
| R-404A | HP-62 | 502, 12, 500 | R, N |
| R-406A | GHG | 12, 500 | R |
| R-407A, R-407B | Klea 407A, 407B | 502 | R, N |
| R-408A (HCFC Blend Epsilon) | 502 | R | |
| R-409A (HCFC Blend Gamma) | 12 | R | |
| R-411A, R-411B | 12, 500, 502 | R, N | |
| R-507 | AZ-50 | 502 | R, N |
| Free Zone (HCFC Blend Delta) | Free Zone / RB-276 | 12 | R, N |
| Freeze 12 | Freeze 12 | 12 | R, N |
| FRIGC FR-12 (HCFC Blend Beta) | FRIGC FR-12 | 12, 500 | R, N |
| GHG-X4 | GHG-X4, Autofrost, Chill-it | 12, 500 | R, N |
| GHG-X5 | GHG-X5 | 12, 500 | R, N |
| GHG-HP (HCFC Blend Lambda) | GHG-HP | 12 | R, N |
| G2018C | G2018C | 12, 500, 502 | R, N |
| Hot Shot | Hot Shot, Kar Kool | 12, 500 | R, N |
| HCFC-22/HCFC-142b | 12 | R, N | |
| THR-04 | THR-04 | 502 | R, N |
| FOR12A | FOR12A | 12 | R, N |
| FOR12B | FOR12B | 12 | R, N |
| SP34E | SP34E | 12 | R, N |
| HFC-134a/HBr (92/8) | 12, 502 | N | |
| Direct Nitrogen Expansion | all | N | |
| Cryogenic Transport Refrigeration System | Cryo-Mechanical | 12, 502 | N |
| Stirling Cycle | all | N | |
| Self-chilling cans using CO 2 | 12, 500, 502 | N | |
| RS-24 (2002 formulation) | 12 | R, N | |
| NU-22 | NU-22 | 502 | R, N |
| R-407C | Suva 407C, Klea 407C | 502 | R, N |
| R-421B | Choice R421B | 12, 502 | R, N |
| R-426A | RS-24 | 12 | R, N |
| R-422C | ICOR XLT1 | 502 | R, N |
| R-428A | RS-52 | 502 | R, N |
| KDD6 | KDD6 | 12 | R, N |
| R-407D | 12 | R, N | |
| Hot Shot 2 | Hot Shot 2 | 12, 500, 502 | R |
Key: R = Retrofit Uses, N = New
Uses
Acceptable Substitutes for HCFCs (class II ODS) in Refrigerated Transport
| Substitute (Name Used in the Federal Register) | Trade Name | Refrigerant Being Replaced | Retrofit/ New |
|---|---|---|---|
| R-410A | AZ-20, Suva 9100, Puron | 22 and blends containing HCFCs | N |
| R-410B | 22, blends containing 22 and/or 142b | N | |
| THR-03 | 22 | R, N | |
| ISCEON 59, NU-22, R-417A | ISCEON 59, NU-22 | 22, blends containing 22 and/or 142b | R, N |
| R-407C | Suva 9000, Klea 66 | 22 and blends containing HCFCs | R, N |
| R-507, R-507A | AZ-50 | 22 and blends containing HCFCs | R, N |
| R-404A | HP62 | 22 and blends containing HCFCs | R, N |
| R-125/134a/600a (28.1/70.0/1.9) | NU-22 old composition | 22, blends containing 22 and/or 142b | R, N |
| Self-Chilling cans using recycled CO2 | 22 | R, N | |
| RS-44 (2003 formulation) | 22, blends containing 22 and/or 142b | R, N | |
| ISCEON 79, R-422A | ISCEON 79 | 22 and blends containing HCFCs | R, N |
| R-421A | Choice R421A | 22, blends containing 22 and/or 142b | R, N |
| R-421B | Choice R421B | 22, blends containing 22 and/or 142b | R, N |
| R-422D | ISCEON MO29 | 22, blends containing 22 and/or 142b | R, N |
| R-424A | RS-44 | 22, blends containing 22 and/or 142b | R, N |
| R-426A | RS-24 | 22, blends containing 22 and/or 142b | R, N |
| KDD5, R-438A | ISCEON MO99 | 22, blends containing 22 and/or 142b | R, N |
| R-434A | RS-45 | 22, blends containing 22 and/or 142b | R, N |
| R-428A | RS-52 | 22 and blends containing HCFCs | R, N |
| R-125/290/134a/600a (55.0/1.0/42.5/1.5) | ICOR AT-22 | 22, blends containing 22 and/or 142b | R, N |
| R-422B | XAC1, NU-22B | 22, blends containing 22 and/or 142b | R, N |
| R-422C | XLT1 | 22, blends containing 22 and/or 142b | R, N |
| R-407A | KLEA 60, KLEA 407A | 22 and blends containing HCFCs | R, N |
| HFC-134a | 22, blends containing 22 and/or 142b | R, N | |
| RS-24 (2002 formulation) | 22, blends containing 22 and/or 142b | R, N | |
| R-407D | 22, blends containing 22 and/or 142b | R, N | |
| R-407B | 22, blends containing 22 and/or 142b | R, N | |
| Cryogenic system using recaptured liquid CO2 or liquid nitrogen | 22, blends containing 22 and/or 142b | N | |
| Direct nitrogen expansion | 22, blends containing 22 and/or 142b | N | |
| SP34E | SP34E | 22, blends containing 22 and/or 142b | R, N |
| Stirling cycle | 22, blends containing 22 and/or 142b | N | |
| Hot Shot 2 | Hot Shot 2 | 22, blends containing 22 and/or 142b | R |
| R-407F | Genetron Performax LT | 22, blends containing 22 and/or 142b | R, N |
Key: R = Retrofit Uses, N = New
Uses