Chemical Testing for Potential Hormone Effects Ordered
EPA has begun issuing the first test orders for pesticides to be screened for their potential effects on the endocrine system. Endocrine disruptors are chemicals that interact with and disrupt the hormones produced or secreted by the human or animal endocrine system, which regulates growth, metabolism and reproduction. Read EPA's press release. The thirty-one pesticides that will be screened under the EDSP so far are:
Chemical Name |
CAS Number |
| 2,4-D | 94-75-7 |
| Acephate | 30560-19-1 |
| Atrazine | 1912-24-9 |
| Benfluralin | 1861-40-1 |
| Bifenthrin | 82657-04-3 |
| Carbamothioic acid, dipropyl-, S-ethyl ester (EPTC) | 759-94-4 |
| Carbaryl | 63-25-2 |
| Carbofuran | 1563-66-2 |
| Chlorpyrifos | 2921-88-2 |
| Chlorthal-Dimethyl (DCPA) | 1861-32-1 |
| Cyfluthrin | 68359-37-5 |
| Cypermethrin | 52315-07-8 |
| Diazinon | 333-41-5 |
| Dimethoate | 60-51-5 |
| Disulfoton | 298-04-4 |
| Ethoprop | 13194-48-4 |
| Esfenvalerate | 66230-04-4 |
| Fenbutatin oxide | 13356-08-6 |
| Malathion | 121-75-5 |
| Methamidophos | 10265-92-6 |
| Methidathion | 950-37-8 |
| Methomyl | 16752-77-5 |
| Methyl parathion | 298-00-0 |
| Norflurazon | 27314-13-2 |
| Oxamyl | 23135-22-0 |
| Permethrin | 52645-53-1 |
| Phosmet | 732-11-6 |
| Piperonyl butoxide | 51-03-6 |
| Propargite | 2312-35-8 |
| Resmethrin | 10453-86-8 |
| Tetrachlorvinphos/Gardona | 22248-79-9 |
Details on the status of the test orders, including the order issuance date, the recipient(s) of the order, each order recipient's response and the order due date (PDF) (32 pp, 136KB, About PDF). EPA intends to update the list with subsequent publications and postings as appropriate.
Examples of FFDCA 408(p) Orders:
- Sample FFDCA 408(p) Order for Pesticide Registrants (PDF) (16 pp, 197K, About PDF)
- Sample FFDCA 408(p) Order for Pesticide Inert Ingredients (PDF) (16 pp, 211K, About PDF)
As described in the October 21, 2009 Federal Register Notice, EPA intends to issue test orders requiring Tier 1 screening for the first group of 67 chemicals between October 29, 2009, and February 26, 2010. The EDSP Tier 1 screening data required to satisfy an order are due within two years of the date of issuance of the order.
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