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Substitutes in Motor Vehicle Air Conditioners

NOTE: All substitutes in this sector are acceptable subject to use conditions. See SNAP Regulations for more information.

Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is also available.

Unacceptable substitutes

Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.

Substitutes Acceptable Subject to Use Conditions for CFC-12 (class I ODS) in MVACs*

Substitute (Name Used in the Federal Register) Trade Name Retrofit/ New
HCFC-22   R, N (Buses Only)
HFC-134a   R, N
HFC-152a1   N
R-406A GHG, GHG-X3, GHG-12, McCool, Autofrost X3 R, N
GHG-X4, R-414A (HCFC Blend Xi) GHG-X4, Autofrost, Chill-it, Autofrost X4 R, N
Small auxiliary power units that include an engine, electrical alternator, water pump, air conditioning compressor and a heat exchanger used in tractor trailers in conjunction with passenger compartment climate control systems that already use an acceptable substitute refrigerant.   R, N
Hot Shot, R-414B (HCFC Blend Omicron) Hot Shot, Kar Kool R, N
FRIGC FR-12, (HCFC Blend Beta), R-416A FRIGC FR-12 R, N
Free Zone, (HCFC Blend Delta) Free Zone / RB-276 R, N
Freeze 12 Freeze 12 R, N
GHG-X5 GHG-X5 R, N
GHG-HP (HCFC Blend Lambda) GHG-HP R, N
Ikon 12, Ikon A (Blend Zeta) Ikon 12 R, N
SP34E SP34E R, N
Stirling Cycle   N
R-744 (Carbon Dioxide, CO2)3   N
RS-24 RS-24 R, N
Evaporative Cooling   N
R-426A RS-24 R, N
HFO-1234yf2   N
Key: R = Retrofit Uses, N = New Uses

* Refrigerated cargo areas, buses, and passenger trains using HCFC-22 are not included in the definitions of “motor vehicle air-conditioners” or “motor vehicle-like air-conditioners” under EPA regulations for servicing of motor vehicle air conditioners.

1 See use conditions for HFC-152a at 73 FR 33304.

2 See use conditions for HFO-1234yf at 76 FR 17488.

3 See use conditions for R-744 (Carbon Dioxide, CO2) .

Substitutes Acceptable for HCFCs (class II ODS) for Buses and Passenger Trains*

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New
Blend of R-125/R-134a/R-600a (28.1/70.0/1.9) NU-22 old composition 22, blends containing 22 and/or 142b R, N
HFC-134a   22, blends containing 22 and/or 142b R, N
R-407C Suva 407C, Klea 407C 22, blends containing 22 and/or 142b R, N
R-410A AZ-20; Puron 22, blends containing 22 and/or 142b N
R-422D ISCEON MO29 22, blends containing 22 and/or 142b R, N
KDD5, R-438A ISCEON MO99 22, blends containing 22 and/or 142b R, N
ISCEON 59, NU-22, R-417A ISCEON 59, NU-22 22, blends containing 22 and/or 142b R, N
R-422B XAC1, NU-22B 22, blends containing 22 and/or 142b R, N
R-427A Forane 427A 22, blends containing 22 and/or 142b R
R-424A RS-44 22, blends containing 22 and/or 142b R, N
R-434A RS-45 22, blends containing 22 and/or 142b R, N
RS-24 (2002 formulation) RS-24 (2002 formulation) 22, blends containing 22 and/or 142b R, N
SP34E SP34E 22, blends containing 22 and/or 142b R, N
Stirling engine   22, blends containing 22 and/or 142b N
Evaporative cooling   22, blends containing 22 and/or 142b N
R-426A   22, blends containing 22 and/or 142b R, N
R-407F   Genetron Performax LT 22, blends containing 22 and/or 142b R, N

Key: R = Retrofit Uses, N = New Uses

* Refrigerated cargo areas, buses, and passenger trains using HCFC-22 are not included in the definitions of “motor vehicle air-conditioners” or “motor vehicle-like air-conditioners” under EPA regulations for servicing of motor vehicle air conditioners.

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