Toxics Release Inventory (TRI) Program
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Toxics Release Inventory - Chemical Hazard Information Profile |
TRI-CHIP Basic Information
TRI's searchable database system that contains hazard information for chemicals included on the Toxics Release Inventory. Searches can be customized across a single chemical, a set of specific chemicals or a TRI chemical category of interest. Click here for instructions on downloading and installing TRI-CHIP version 2.05. Your comments concerning the applicability, user friendliness or potential improvements of TRI-CHIP are greatly appreciated. Please send comments to: John Scalera and Daniel R. Bushman, Ph.D of the Office of Environmental Information /Office of Information Analysis and Access.
TRI-CHIP allows the user to:
- Easily search for toxicity information on TRI chemicals from multiple information sources
- Use built in queries to identify chemicals that meet quantitative toxicity criteria such as a lowest observed adverse effect levels (LOAEL) above a specified value
- Identify all TRI chemicals associated with a critical adverse human health effect of interest
- Print customized chemical toxicity profile reports
- Readily move in and out of Web sites where additional chemical toxicity information can be found
- The screen shot below depicts a typical TRI-CHIP search page
TRI-CHIP contains hazard information for TRI chemicals from the following sources:
- Toxics Release Inventory (TRI) Federal Register Notices
- Integrated Risk Information System (IRIS)
- EPA Office of Pesticide Programs (OPP) Registration Documents
- Agency for Toxic Substances and Disease Registry (ATSDR)
- California Environmental Protection Agency (Cal/EPA) - Office of Environmental Health Hazard Assessment (OEHHA)
- National Toxicology Program (NTP) – 11th Report on Carcinogens
- International Agency for Research on Cancer (IARC)
TRI-CHIP Screen shot

TRI-CHIP At-A-Glance
| Available Toxicity Information | Information Sources | ||||||
|---|---|---|---|---|---|---|---|
| TRI | IRIS | OPP | ATSDR | CalEPA | NTP | IARC | |
| Date reporting required | ![]() |
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| Listing criteria basisa | ![]() |
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| Toxicity criteriab | |||||||
| Inhalation | ![]() |
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| Oral | ![]() |
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| Cancer | |||||||
| Riskc | ![]() |
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| Weight-of-evidence | ![]() |
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| Exposure levelsd | ![]() |
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| Notification levelse | ![]() |
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| Toxicity Dataf | |||||||
| Target tissues | ![]() |
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| Species | ![]() |
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| Experimental values and benchmark dosesg | ![]() |
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- Chemicals assessed for addition to the TRI list in Federal Register (FR) 1992 and 1994 rulings.
- Reference dose (RfD), reference concentration (RfC), minimal risk level (MRL), no significant risk level (NSRL), maximum allowable daily level (MADL)
- Quantitative cancer assessment (oral slope factor, drinking water unit risk, inhalation unit risk, inhalation slope factor)
- Reference exposure level (REL)
- Public health goal (PHG)
- For critical effects (non-cancer and cancer)
- No observed adverse effect level (NOAEL), lowest observed adverse effect level (LOAEL), benchmark dose (BMD)


