Basic Course: Supplemental Topics
Risk Assessment for Cancer Effects (Linear): Other Terms in the Equation
The remaining terms in the equation for deriving linear cancer human health AWQC are consistent across all three equations.

Exposure
BW = Human Body Weight (70 kg for average adult)
DI = Drinking Water Intake (2 L/day for average adult)
FI = Fish Intake (kg/day)
Bioaccumulation
BAF = Bioaccumulation Factor (L/kg)
Note that details about exposure and bioaccumulation terms are presented later in this module, following this section that focuses on the three equations used to calculate human health AWQC.
Key Point. Remember the RSD term in the equation is the risk you select (10-6 or 10-5, as long as the exposed population risk is not greater then
10-4) divided by the cancer slope factor. IRIS is the best source of CSF data for chemical contaminants.
Disclaimer:
For informational purposes only–Not official statements of EPA policy.
Course Navigation
- Listing Impaired Waters and Developing TMDLs
- Monitoring & Assessment
- NPDES Permit Program
- Human Health Ambient Water Quality Criteria
- Introduction
- Historical Approach to Human Health Criteria Development
- Updated Approach
- Quantitative Risk Assessment
- Toxicological Parameter for Noncancer Effects
- Risk Assessment for Noncancer Effects
- Toxicological Parameter for Cancer Effects (Linear)
- Risk Assessment for Cancer Effects (Linear)
- Toxicological Parameter for Cancer Effects (Nonlinear)
- Risk Assessment for Cancer Effects (Nonlinear)
- Exposure Assessment
- Bioaccumulation
- Summary
- Quiz
- Aquatic Life Criteria
![[logo] US EPA](http://www.epa.gov/epafiles/images/logo_epaseal.gif)