Computational Toxicology and Exposure Communities of Practice - ECOTOXicology Knowledgebase: Update with Ecologically Relevant Data for Emerging Contaminants
Date and Time
11:00 am - 12:00 pm EDT
Location
United States
Event Type
Description
Topic: ECOTOXicology Knowledgebase: Update with Ecologically Relevant Data for Emerging Contaminants
Who: Jennifer Olker, EPA ORD Center for Computational Toxicology and Exposure
When: May 23, 11 – 12 p.m. ET
Where: Please register via Zoom. Don't forget to download the calendar hold which contains your personalized Zoom link. You will need this link to join the webinar.
Topic overview:
The ECOTOXicology Knowledgebase (ECOTOX) has been locating and curating ecologically relevant toxicity data for over 30 years and is now a nationally and internationally recognized source of single-chemical toxicity test results for aquatic and terrestrial organisms. ECOTOX uses systematic and transparent procedures to conduct comprehensive literature searches, screen references, apply acceptance criteria, and extract all pertinent study and effects information. The toxicity results within ECOTOX are used by multiple partners and applications, and thus ECOTOX procedures extract and provide data in a format suitable for pre-decisional analysis with sufficient details on test compound(s), methods, and biological effects for users (e.g., USEPA program offices) to evaluate study quality and synthesize the results for their specific applications. The structured empirical toxicity data in ECOTOX support chemical risk assessments and data gap identification, as well as the development of computational models and the development, evaluation, and adoption of new approach methodologies. Currently, the publicly accessible ECOTOX website (www.epa.gov/ecotox) includes data for more than 12,000 chemicals from over 54,000 references. Literature searches, reviews, and data curation are on-going, with focus on chemicals of priority for agency assessments and research. This presentation describes the ECOTOX literature search and data curation pipeline and provides examples of toxicity data updates for several contaminants of emerging and immediate concern, including PFAS, Cyanotoxins, and 6PPD-quinone.